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Title

Measuring Estrogens at low levels in plasma

Summary in this technical brief, the focus of the measurement procedure was on sample pretreatment and high sensitivity mass spectrometry. The Online SPE approach described herein reduces the likelihood of measurement artifacts such as matrix effects and ion suppression. Rapid, quantitation of the estrogen hormones estrone and Estradiol at low concentrations has been demonstrated
Category 2. Symbiosis Application Notes
These are application notes that have been made in our application lab. They were based on customer demo's and customer method development requests. They include sorbent screening, a calibration curve and are optimized for carry over. They are not always (completely) validated
 
Matrix Plasma
Market OSM Clinical
Cartridge Waters MassTrak C18 Online SPE Cartridges
Detection Waters XEVO TQ-S
Compounds Estradiol, Estrone
Compound Group Estrogens
Sample_volume 250ÁL
 
Contact Laura Owen and Brian Keevil
Account University Hospital South Manchester, UK
Published poster technical Brief
Date 4-8-2015
  Read PDF document
 
Remarks

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Status published