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Using Online SPE to Quickly Develop and Optimize LC/MS Sample Preparation Methods

Summary Traditionally, method development for SPE sample preparation has involved changing a single experimental variable and testing the effect of that change on SPE performance. T his approach of testing single variables in isolation is time consuming and often does not result in an optimized or robust method. The MassTrakô Online SPE Analyzer facilitates the use of Design of Experiments (DoE) techniques to significantly improve sample preparation method development and optimization. The MassTrak Online SPE Analyzer can be used to help identify critical experimental variables Once identified, the system can then simultaneously test a number of those important variables to quickly develop an optimized SPE sample preparation method.
Category 2. Symbiosis Application Notes
These are application notes that have been made in our application lab. They were based on customer demo's and customer method development requests. They include sorbent screening, a calibration curve and are optimized for carry over. They are not always (completely) validated
Market OSM Clinical
Compound Group
Account Waters Corporation
Published Product Solution
Date 4-8-2015
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