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Using Online SPE to Improve Clinical LC/MS Assays

Summary To address many of the performance and productivity issues that are associated with LC /MS sample preparation, the MassTrakô Online SPE Analyzer has been developed to effectively integrate SPE sample preparation with LC /MS analysis in a single platform. T he MassTrak Online SPE Analyzer uses advanced fluidics and single use SPE cartridge technology to seamlessly automate all of the steps required for SPE sample preparation and subsequent LC /MS analysis. T he system effectively and efficiently uses online SPE to remove the majority of the background interferences and ion suppression effects for LC /MS analysis often seen in clinical samples. As demonstrated here, using the MassTrak Online SPE Analyzer can have significant effects on the sensitivity and robustness of LC /MS assay results.1
Category 2. Symbiosis Application Notes
These are application notes that have been made in our application lab. They were based on customer demo's and customer method development requests. They include sorbent screening, a calibration curve and are optimized for carry over. They are not always (completely) validated
Market OSM Clinical
Compound Group
Account Waters Corporaiton
Published Product Solution
Date 4-8-2015
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